Macroscopic descriptions in anatomic pathology play a crucial role in the evaluation of tissue samples and in diagnosis and treatment decisions of patients. This applies to biological specimens in both animal and human oncology. The presented DATP-IU dataset aims to serve as a pioneering effort, starting with animal samples, to create a digital atlas of histopathological tissue specimens at the macroscopic level, enriched with quantitative sensory data. The image and ultrasound data were obtained from formalin-fixed histological animal tissues of varying sizes, types, and origins. The data were analyzed using a rotary-stage coordinate system and compared with manual caliper measurements of the same calibration pattern. The average Z absolute error is 1.02%, and sub-millimeter accuracy is maintained across all camera distances. The automatic regulation of yaw angles via a LabVIEW routine enhanced both accuracy and repeatability by eliminating manual errors and ensuring consistent angular adjustments. The presented DATP-IU dataset offers an innovative approach to making pathology assessments more accurate, reproducible, and accessible.

Descriptor: Digital Dataset of Animal Tissues for Macroscopic Pathology in Cancer: Image and Ultrasound Data (DATP-IU)

Fabrizia Auletta;Marton C. Mezei;Ilaria Benedetti;Calogero M. Oddo
2026-01-01

Abstract

Macroscopic descriptions in anatomic pathology play a crucial role in the evaluation of tissue samples and in diagnosis and treatment decisions of patients. This applies to biological specimens in both animal and human oncology. The presented DATP-IU dataset aims to serve as a pioneering effort, starting with animal samples, to create a digital atlas of histopathological tissue specimens at the macroscopic level, enriched with quantitative sensory data. The image and ultrasound data were obtained from formalin-fixed histological animal tissues of varying sizes, types, and origins. The data were analyzed using a rotary-stage coordinate system and compared with manual caliper measurements of the same calibration pattern. The average Z absolute error is 1.02%, and sub-millimeter accuracy is maintained across all camera distances. The automatic regulation of yaw angles via a LabVIEW routine enhanced both accuracy and repeatability by eliminating manual errors and ensuring consistent angular adjustments. The presented DATP-IU dataset offers an innovative approach to making pathology assessments more accurate, reproducible, and accessible.
2026
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11382/587995
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